Is there nothing about butternut squash I should be worried about during pregnancy? No, pregnant women can breathe easy with having butternut squash in their diet. It contains folate that helps in the development of the brain and spinal cord of the growing baby and prevents neural tube defects like spina bifida. It is a very good source of beta-carotene, Vitamin C, manganese, magnesium, calcium, and potassium. All of these are known for their goodness when included in the pregnancy diet.